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Targeting activated protein C to treat hemophilia

Hemophilia is a debilitating disease, marked by frequent, painful bleeding events, joint deterioration and early death. All current treatments consist of i.v. infusions of replacement factor or other procoagulant factors, and are incompletely effective, due in part to the short half-lives of the pro...

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Detalles Bibliográficos
Autores principales: Polderdijk, Stéphanie G.I., Baglin, Trevor P., Huntington, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams And Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548501/
https://www.ncbi.nlm.nih.gov/pubmed/28632502
http://dx.doi.org/10.1097/MOH.0000000000000364