Unraveling heme detoxification in the malaria parasite by in situ correlative X-ray fluorescence microscopy and soft X-ray tomography

A key drug target for malaria has been the detoxification pathway of the iron-containing molecule heme, which is the toxic byproduct of hemoglobin digestion. The cornerstone of heme detoxification is its sequestration into hemozoin crystals, but how this occurs remains uncertain. We report new resul...

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Detalles Bibliográficos
Autores principales: Kapishnikov, Sergey, Grolimund, Daniel, Schneider, Gerd, Pereiro, Eva, McNally, James G., Als-Nielsen, Jens, Leiserowitz, Leslie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548722/
https://www.ncbi.nlm.nih.gov/pubmed/28790371
http://dx.doi.org/10.1038/s41598-017-06650-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548722/
https://www.ncbi.nlm.nih.gov/pubmed/28790371
http://dx.doi.org/10.1038/s41598-017-06650-w

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