Modelling the evolution of transcription factor binding preferences in complex eukaryotes

Transcription factors (TFs) exert their regulatory action by binding to DNA with specific sequence preferences. However, different TFs can partially share their binding sequences due to their common evolutionary origin. This “redundancy” of binding defines a way of organizing TFs in “motif families”...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosanova, Antonio, Colliva, Alberto, Osella, Matteo, Caselle, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548724/
https://www.ncbi.nlm.nih.gov/pubmed/28790414
http://dx.doi.org/10.1038/s41598-017-07761-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548724/
https://www.ncbi.nlm.nih.gov/pubmed/28790414
http://dx.doi.org/10.1038/s41598-017-07761-0

Ejemplares similares