Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling

G protein-coupled receptors (GPCRs) constitute the largest family of cell surface receptors. They can exist and act as dimers, but the requirement of dimers for agonist-induced signal initiation and structural dynamics remains largely unknown. Frizzled 6 (FZD(6)) is a member of Class F GPCRs, which...

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Detalles Bibliográficos
Autores principales: Petersen, Julian, Wright, Shane C., Rodríguez, David, Matricon, Pierre, Lahav, Noa, Vromen, Aviv, Friedler, Assaf, Strömqvist, Johan, Wennmalm, Stefan, Carlsson, Jens, Schulte, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548745/
https://www.ncbi.nlm.nih.gov/pubmed/28790300
http://dx.doi.org/10.1038/s41467-017-00253-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548745/
https://www.ncbi.nlm.nih.gov/pubmed/28790300
http://dx.doi.org/10.1038/s41467-017-00253-9

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