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Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling
G protein-coupled receptors (GPCRs) constitute the largest family of cell surface receptors. They can exist and act as dimers, but the requirement of dimers for agonist-induced signal initiation and structural dynamics remains largely unknown. Frizzled 6 (FZD(6)) is a member of Class F GPCRs, which...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548745/ https://www.ncbi.nlm.nih.gov/pubmed/28790300 http://dx.doi.org/10.1038/s41467-017-00253-9 |