Cargando…

TRPC6 counteracts TRPC3-Nox2 protein complex leading to attenuation of hyperglycemia-induced heart failure in mice

Excess production of reactive oxygen species (ROS) caused by hyperglycemia is a major risk factor for heart failure. We previously reported that transient receptor potential canonical 3 (TRPC3) channel mediates pressure overload-induced maladaptive cardiac fibrosis by forming stably functional compl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oda, Sayaka, Numaga-Tomita, Takuro, Kitajima, Naoyuki, Toyama, Takashi, Harada, Eri, Shimauchi, Tsukasa, Nishimura, Akiyuki, Ishikawa, Tatsuya, Kumagai, Yoshito, Birnbaumer, Lutz, Nishida, Motohiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548754/ https://www.ncbi.nlm.nih.gov/pubmed/28790356 http://dx.doi.org/10.1038/s41598-017-07903-4

Ejemplares similares

TRPC3 Channels in Cardiac Fibrosis
por: Numaga-Tomita, Takuro, et al.
Publicado: (2017)

TRPC channels in exercise-mimetic therapy
por: Numaga-Tomita, Takuro, et al.
Publicado: (2018)

TRPC3-Nox2 axis mediates nutritional deficiency-induced cardiomyocyte atrophy
por: Sudi, Suhaini Binti, et al.
Publicado: (2019)

TRPC Channels in Cardiac Plasticity
por: Numaga-Tomita, Takuro, et al.
Publicado: (2020)

TRPC3-GEF-H1 axis mediates pressure overload-induced cardiac fibrosis
por: Numaga-Tomita, Takuro, et al.
Publicado: (2016)

TRPC3 positively regulates reactive oxygen species driving maladaptive cardiac remodeling
por: Kitajima, Naoyuki, et al.
Publicado: (2016)

TRPC5-eNOS Axis Negatively Regulates ATP-Induced Cardiomyocyte Hypertrophy
por: Sunggip, Caroline, et al.
Publicado: (2018)

A TRPC3/6 Channel Inhibitor Promotes Arteriogenesis after Hind-Limb Ischemia
por: Shimauchi, Tsukasa, et al.
Publicado: (2022)

The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing
por: Sexton, Jane E., et al.
Publicado: (2016)

Myocardial TRPC6-mediated Zn(2+) influx induces beneficial positive inotropy through β-adrenoceptors
por: Oda, Sayaka, et al.
Publicado: (2022)

Crucial Role of TRPC1 and TRPC4 in Cystitis-Induced Neuronal Sprouting and Bladder Overactivity
por: Boudes, Mathieu, et al.
Publicado: (2013)

Inhibition of transient receptor potential cation channel 6 promotes capillary arterialization during post‐ischaemic blood flow recovery
por: Numaga‐Tomita, Takuro, et al.
Publicado: (2022)

TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells
por: Quick, Kathryn, et al.
Publicado: (2012)

Corticolimbic Expression of TRPC4 and TRPC5 Channels in the Rodent Brain
por: Fowler, Melissa A., et al.
Publicado: (2007)

TRPC1 regulates calcium‐activated chloride channels in salivary gland cells
por: Sun, Yuyang, et al.
Publicado: (2015)

Deep Transcriptomic Profiling of M1 Macrophages Lacking Trpc3
por: Kumarasamy, Sivarajan, et al.
Publicado: (2017)

Novel Targets for Stroke Therapy: Special Focus on TRPC Channels and TRPC6
por: Liu, Lu, et al.
Publicado: (2020)

TRPC3 Regulates Islet Beta‐Cell Insulin Secretion
por: Rached, Gaëlle, et al.
Publicado: (2023)

Cardioprotection by Klotho through downregulation of TRPC6 channels in the mouse heart
por: Xie, Jian, et al.
Publicado: (2012)

Store‐operated interactions between plasmalemmal STIM1 and TRPC1 proteins stimulate PLCβ1 to induce TRPC1 channel activation in vascular smooth muscle cells
por: Shi, Jian, et al.
Publicado: (2016)

TRPC Channels in the SOCE Scenario
por: Lopez, Jose J., et al.
Publicado: (2020)

RNA-seq analysis reveals TRPC genes to impact an unexpected number of metabolic and regulatory pathways
por: Formoso, Karina, et al.
Publicado: (2020)

Increasing the expression of calcium-permeable TRPC3 and TRPC7 channels enhances constitutive secretion
por: Lavender, Verna, et al.
Publicado: (2008)

The roles of G proteins in the activation of TRPC4 and TRPC5 transient receptor potential channels
por: Kim, Hana, et al.
Publicado: (2012)

TRPC3, but not TRPC1, as a good therapeutic target for standalone or complementary treatment of DMD
por: Creisméas, Anna, et al.
Publicado: (2021)

TRPC3 and NALCN channels drive pacemaking in substantia nigra dopaminergic neurons
por: Um, Ki Bum, et al.
Publicado: (2021)

TRPC3-Nox2 Protein Complex Formation Increases the Risk of SARS-CoV-2 Spike Protein-Induced Cardiomyocyte Dysfunction through ACE2 Upregulation
por: Kato, Yuri, et al.
Publicado: (2022)

Specific Upregulation of TRPC1 and TRPC5 Channels by Mineralocorticoid Pathway in Adult Rat Ventricular Cardiomyocytes
por: Bartoli, Fiona, et al.
Publicado: (2019)

Analysis of the Effect of the TRPC4/TRPC5 Blocker, ML204, in Sucrose-Induced Metabolic Imbalance
por: Araújo, Mizael C., et al.
Publicado: (2023)

Lipid-independent control of endothelial and neuronal TRPC3 channels by light
por: Tiapko, Oleksandra, et al.
Publicado: (2019)

Contribution of TRPC Channels in Neuronal Excitotoxicity Associated With Neurodegenerative Disease and Ischemic Stroke
por: Jeon, Jaepyo, et al.
Publicado: (2021)

Heteromeric TRPV4/TRPC1 channels mediate calcium-sensing receptor-induced relaxations and nitric oxide production in mesenteric arteries: comparative study using wild-type and TRPC1(−/-) mice
por: Greenberg, Harry Z.E., et al.
Publicado: (2019)

TRPC1 participates in the HSV-1 infection process by facilitating viral entry
por: He, DongXu, et al.
Publicado: (2020)

TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response
por: Weber, Evan W., et al.
Publicado: (2015)

TRPC1: Getting physical in space
por: Ambudkar, Indu S
Publicado: (2013)

TRPC expression in mesenchymal stem cells
por: Torossian, Frederic, et al.
Publicado: (2010)

TRPC Channels in Proteinuric Kidney Diseases
por: Hall, Gentzon, et al.
Publicado: (2019)

Cocaine self-administration in mice with forebrain knock-down of trpc5 ion channels
por: Pomrenze, Matthew B, et al.
Publicado: (2013)

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A
por: Cheung, Sin Ying, et al.
Publicado: (2018)

Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli
por: Ilatovskaya, Daria V., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_598i25a22jfjt5rnevc9kl47lk