Single cardiomyocyte nuclear transcriptomes reveal a lincRNA-regulated de-differentiation and cell cycle stress-response in vivo

Cardiac regeneration may revolutionize treatment for heart failure but endogenous progenitor-derived cardiomyocytes in the adult mammalian heart are few and pre-existing adult cardiomyocytes divide only at very low rates. Although candidate genes that control cardiomyocyte cell cycle re-entry have b...

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Detalles Bibliográficos
Autores principales: See, Kelvin, Tan, Wilson L. W., Lim, Eng How, Tiang, Zenia, Lee, Li Ting, Li, Peter Y. Q., Luu, Tuan D. A., Ackers-Johnson, Matthew, Foo, Roger S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548780/
https://www.ncbi.nlm.nih.gov/pubmed/28790305
http://dx.doi.org/10.1038/s41467-017-00319-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548780/
https://www.ncbi.nlm.nih.gov/pubmed/28790305
http://dx.doi.org/10.1038/s41467-017-00319-8

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