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Single cardiomyocyte nuclear transcriptomes reveal a lincRNA-regulated de-differentiation and cell cycle stress-response in vivo
Cardiac regeneration may revolutionize treatment for heart failure but endogenous progenitor-derived cardiomyocytes in the adult mammalian heart are few and pre-existing adult cardiomyocytes divide only at very low rates. Although candidate genes that control cardiomyocyte cell cycle re-entry have b...
Autores principales: | See, Kelvin, Tan, Wilson L. W., Lim, Eng How, Tiang, Zenia, Lee, Li Ting, Li, Peter Y. Q., Luu, Tuan D. A., Ackers-Johnson, Matthew, Foo, Roger S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548780/ https://www.ncbi.nlm.nih.gov/pubmed/28790305 http://dx.doi.org/10.1038/s41467-017-00319-8 |
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