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Differentiation impairs Bach1 dependent HO-1 activation and increases sensitivity to oxidative stress in SH-SY5Y neuroblastoma cells

Neuronal adaptation to oxidative stress is crucially important in order to prevent degenerative diseases. The role played by the Nrf2/HO-1 system in favoring cell survival of neuroblastoma (NB) cells exposed to hydrogen peroxide (H(2)O(2)) has been investigated using undifferentiated or all-trans re...

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Detalles Bibliográficos
Autores principales: Piras, Sabrina, Furfaro, Anna Lisa, Brondolo, Lorenzo, Passalacqua, Mario, Marinari, Umberto Maria, Pronzato, Maria Adelaide, Nitti, Mariapaola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548785/
https://www.ncbi.nlm.nih.gov/pubmed/28790431
http://dx.doi.org/10.1038/s41598-017-08095-7