A Plasmodium yoelii HECT-like E3 ubiquitin ligase regulates parasite growth and virulence

Infection of mice with strains of Plasmodium yoelii parasites can result in different pathology, but molecular mechanisms to explain this variation are unclear. Here we show that a P. yoelii gene encoding a HECT-like E3 ubiquitin ligase (Pyheul) influences parasitemia and host mortality. We genetica...

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Detalles Bibliográficos
Autores principales: Nair, Sethu C., Xu, Ruixue, Pattaradilokrat, Sittiporn, Wu, Jian, Qi, Yanwei, Zilversmit, Martine, Ganesan, Sundar, Nagarajan, Vijayaraj, Eastman, Richard T., Orandle, Marlene S., Tan, John C., Myers, Timothy G., Liu, Shengfa, Long, Carole A., Li, Jian, Su, Xin-zhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548792/
https://www.ncbi.nlm.nih.gov/pubmed/28790316
http://dx.doi.org/10.1038/s41467-017-00267-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548792/
https://www.ncbi.nlm.nih.gov/pubmed/28790316
http://dx.doi.org/10.1038/s41467-017-00267-3

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