Evolution of new regulatory functions on biophysically realistic fitness landscapes

Gene expression is controlled by networks of regulatory proteins that interact specifically with external signals and DNA regulatory sequences. These interactions force the network components to co-evolve so as to continually maintain function. Yet, existing models of evolution mostly focus on isola...

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Detalles Bibliográficos
Autores principales: Friedlander, Tamar, Prizak, Roshan, Barton, Nicholas H., Tkačik, Gašper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548793/
https://www.ncbi.nlm.nih.gov/pubmed/28790313
http://dx.doi.org/10.1038/s41467-017-00238-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548793/
https://www.ncbi.nlm.nih.gov/pubmed/28790313
http://dx.doi.org/10.1038/s41467-017-00238-8

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