Conformational modulation of influenza virus hemagglutinin: characterization and in vivo efficacy of monomeric form

Mutational changes that mostly occur at the head region of hemagglutinin (HA) lead to the emergence of new epidemic influenza viruses, whereas HA antigens have been modified to generate broadly neutralizing antibodies toward highly conserved epitopes in the HA stem. Interestingly, a recent analysis...

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Detalles Bibliográficos
Autores principales: Seok, Jong Hyeon, Kim, Jeongwon, Lee, Dan Bi, Cho, Ki Joon, Lee, Ji-Hye, Bae, Garam, Chung, Mi Sook, Kim, Kyung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548806/
https://www.ncbi.nlm.nih.gov/pubmed/28790432
http://dx.doi.org/10.1038/s41598-017-08021-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548806/
https://www.ncbi.nlm.nih.gov/pubmed/28790432
http://dx.doi.org/10.1038/s41598-017-08021-x

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