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Conformational modulation of influenza virus hemagglutinin: characterization and in vivo efficacy of monomeric form
Mutational changes that mostly occur at the head region of hemagglutinin (HA) lead to the emergence of new epidemic influenza viruses, whereas HA antigens have been modified to generate broadly neutralizing antibodies toward highly conserved epitopes in the HA stem. Interestingly, a recent analysis...
Autores principales: | Seok, Jong Hyeon, Kim, Jeongwon, Lee, Dan Bi, Cho, Ki Joon, Lee, Ji-Hye, Bae, Garam, Chung, Mi Sook, Kim, Kyung Hyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548806/ https://www.ncbi.nlm.nih.gov/pubmed/28790432 http://dx.doi.org/10.1038/s41598-017-08021-x |
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