Shedding Light on Alzheimer’s β-Amyloidosis: Photosensitized Methylene Blue Inhibits Self-Assembly of β-Amyloid Peptides and Disintegrates Their Aggregates

Abnormal aggregation of β-amyloid (Aβ) peptides is a major hallmark of Alzheimer’s disease (AD). In spite of numerous attempts to prevent the β-amyloidosis, no effective drugs for treating AD have been developed to date. Among many candidate chemicals, methylene blue (MB) has proved its therapeutic...

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Detalles Bibliográficos
Autores principales: Lee, Byung Il, Suh, Yoon Seok, Chung, You Jung, Yu, Kweon, Park, Chan Beum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548810/
https://www.ncbi.nlm.nih.gov/pubmed/28790398
http://dx.doi.org/10.1038/s41598-017-07581-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548810/
https://www.ncbi.nlm.nih.gov/pubmed/28790398
http://dx.doi.org/10.1038/s41598-017-07581-2

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