Cargando…

Shedding Light on Alzheimer’s β-Amyloidosis: Photosensitized Methylene Blue Inhibits Self-Assembly of β-Amyloid Peptides and Disintegrates Their Aggregates

Abnormal aggregation of β-amyloid (Aβ) peptides is a major hallmark of Alzheimer’s disease (AD). In spite of numerous attempts to prevent the β-amyloidosis, no effective drugs for treating AD have been developed to date. Among many candidate chemicals, methylene blue (MB) has proved its therapeutic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Byung Il, Suh, Yoon Seok, Chung, You Jung, Yu, Kweon, Park, Chan Beum
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548810/ https://www.ncbi.nlm.nih.gov/pubmed/28790398 http://dx.doi.org/10.1038/s41598-017-07581-2

Ejemplares similares

Magnetoelectric dissociation of Alzheimer’s β-amyloid aggregates
por: Jang, Jinhyeong, et al.
Publicado: (2022)

In vitro Effect of Photodynamic Therapy with Curcumin and Methylene Blue Photosensitizers on Staphylococcus Aureus
por: Entezari, Sarvin, et al.
Publicado: (2022)

Modified amyloid variants in pathological subgroups of β‐amyloidosis
por: Gerth, Janina, et al.
Publicado: (2018)

Jowiseungchungtang Inhibits Amyloid-β Aggregation and Amyloid-β-Mediated Pathology in 5XFAD Mice
por: Shin, Soo Jung, et al.
Publicado: (2018)

Trans-Synaptic Spread of Amyloid-β in Alzheimer's Disease: Paths to β-Amyloidosis
por: Pignataro, Annabella, et al.
Publicado: (2017)

Insights from Self-Assembled Aggregates of Amyloid β Peptides on Gold Surfaces
por: Dey, Chinmay, et al.
Publicado: (2022)

Evaluation of Eosin-Methylene Blue as a Photosensitizer for Larval Control of Aedes aegypti by a Photodynamic Process
por: Lima, Alessandra R., et al.
Publicado: (2018)

Different Amyloid-β Self-Assemblies Have Distinct Effects on Intracellular Tau Aggregation
por: Shin, Woo Shik, et al.
Publicado: (2019)

Methylene blue inhibits nucleation and elongation of SOD1 amyloid fibrils
por: Musteikyte, Greta, et al.
Publicado: (2020)

Bleomycin modulates amyloid aggregation in β-amyloid and hIAPP
por: Kumari, Anchala, et al.
Publicado: (2020)

Age-Dependent Protein Aggregation Initiates Amyloid-β Aggregation
por: Groh, Nicole, et al.
Publicado: (2017)

Tau aggregation and its interplay with amyloid-β
por: Nisbet, Rebecca M., et al.
Publicado: (2014)

The Effects of Latrepirdine on Amyloid-β Aggregation and Toxicity
por: Porter, Tenielle, et al.
Publicado: (2016)

Nanomaterials for Modulating the Aggregation of β-Amyloid Peptides
por: Huang, Yaliang, et al.
Publicado: (2021)

Key Residue for Aggregation of Amyloid-β Peptides
por: Itoh, Satoru G., et al.
Publicado: (2022)

Tricyano-Methylene-Pyridine Based High-Performance Aggregation-Induced Emission Photosensitizer for Imaging and Photodynamic Therapy
por: Wu, Xupeng, et al.
Publicado: (2022)

Effective screen for amyloid β aggregation inhibitor using amyloid β-conjugated gold nanoparticles
por: Han, Sun-Ho, et al.
Publicado: (2011)

Inhibition of Amyloid β-Induced Lipid Membrane Permeation and Amyloid β Aggregation by K162
por: Mrdenovic, Dusan, et al.
Publicado: (2021)

Structural Determinant of β-Amyloid Formation: From Transmembrane Protein Dimerization to β-Amyloid Aggregates
por: Papadopoulos, Nicolas, et al.
Publicado: (2022)

Methylene Blue Dye as Photosensitizer for Scavenger-Less Water Photo Splitting: New Insight in Green Hydrogen Technology
por: Barakat, Nasser A. M., et al.
Publicado: (2022)

Amyloid β-Sheet Mimics that Antagonize Amyloid Aggregation and Reduce Amyloid Toxicity
por: Cheng, Pin-Nan, et al.
Publicado: (2012)

Membrane-Accelerated Amyloid-β Aggregation and Formation of Cross-β Sheets
por: Khondker, Adree, et al.
Publicado: (2017)

Comparative Study of Toluidine Blue O and Methylene Blue Binding to Lysozyme and Their Inhibitory Effects on Protein Aggregation
por: Saha, Baishakhi, et al.
Publicado: (2018)

Unraveling the Early Events of Amyloid-β Protein (Aβ) Aggregation: Techniques for the Determination of Aβ Aggregate Size
por: Pryor, N. Elizabeth, et al.
Publicado: (2012)

Retraction: Different Amyloid-β Self-Assemblies Have Distinct Effects on Intracellular Tau Aggregation
Publicado: (2021)

Food protein-derived amyloids do not accelerate amyloid β aggregation
por: Rahman, M. Mahafuzur, et al.
Publicado: (2023)

Arylamine Analogs of Methylene Blue: Substituent Effect on Aggregation Behavior and DNA Binding
por: Khadieva, Alena, et al.
Publicado: (2021)

Tailoring Hydrophobic Interactions between Probes and Amyloid-β Peptides for Fluorescent Monitoring of Amyloid-β Aggregation
por: Kim, Sonam, et al.
Publicado: (2018)

Amyloid-β peptide 37, 38 and 40 individually and cooperatively inhibit amyloid-β 42 aggregation
por: Braun, Gabriel A., et al.
Publicado: (2022)

Methylene Blue: Revisited
por: Ginimuge, Prashant R., et al.
Publicado: (2010)

Methylene-Blue in Fevers
por: Frost, G. H.
Publicado: (1908)

Effectiveness of methylene blue photosensitizers compared to that of corticosteroids in the management of oral lichen planus: a systematic review and meta-analysis
por: Waingade, Manjushri, et al.
Publicado: (2022)

Apple Procyanidins Suppress Amyloid β-Protein Aggregation
por: Toda, Toshihiko, et al.
Publicado: (2011)

Effect of Metals on Kinetic Pathways of Amyloid-β Aggregation
por: Hane, Francis, et al.
Publicado: (2014)

A discrete mathematical model for the aggregation of β-Amyloid
por: Dayeh, Maher A., et al.
Publicado: (2018)

Modulation of β-amyloid aggregation by graphene quantum dots
por: Liu, Changliang, et al.
Publicado: (2019)

Bacterial Extracellular DNA Promotes β-Amyloid Aggregation
por: Tetz, George, et al.
Publicado: (2021)

Amyloid-β-Derived Peptidomimetics Inhibits Tau Aggregation
por: Gorantla, Nalini V., et al.
Publicado: (2021)

Influence of denaturants on amyloid β42 aggregation kinetics
por: Weiffert, Tanja, et al.
Publicado: (2022)

Methylene blue inhibits NLRP3, NLRC4, AIM2, and non-canonical inflammasome activation
por: Ahn, Huijeong, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_9r23mrhjf73ois9u85bvje4ugp