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The FAD synthetase from the human pathogen Streptococcus pneumoniae: a bifunctional enzyme exhibiting activity-dependent redox requirements

Prokaryotic bifunctional FAD synthetases (FADSs) catalyze the biosynthesis of FMN and FAD, whereas in eukaryotes two enzymes are required for the same purpose. FMN and FAD are key cofactors to maintain the flavoproteome homeostasis in all type of organisms. Here we shed light to the properties of th...

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Detalles Bibliográficos
Autores principales: Sebastián, María, Lira-Navarrete, Erandi, Serrano, Ana, Marcuello, Carlos, Velázquez-Campoy, Adrián, Lostao, Anabel, Hurtado-Guerrero, Ramón, Medina, Milagros, Martínez-Júlvez, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548840/
https://www.ncbi.nlm.nih.gov/pubmed/28790457
http://dx.doi.org/10.1038/s41598-017-07716-5