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Notch Signaling in the Regulation of Hematopoietic Stem Cell

PURPOSE OF REVIEW: Understanding the signaling pathways that govern hematopoietic stem and progenitor cells (HSPCs) is fundamental to uncover their regulation and how this is skewed in hematological malignancies. Whether Notch is necessary for the regulation of mammalian HSPCs is still unclear. We t...

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Detalles Bibliográficos
Autores principales: Lampreia, Fabio Pereira, Carmelo, Joana Gonçalves, Anjos-Afonso, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548842/
https://www.ncbi.nlm.nih.gov/pubmed/28845387
http://dx.doi.org/10.1007/s40778-017-0090-8