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Statistical analysis of mutant allele frequency level of circulating cell-free DNA and blood cells in healthy individuals
Cell-free DNA (cfDNA) in plasma has emerged as a potential important biomarker in clinical diagnostics, particularly in cancer. However, somatic mutations are also commonly found in healthy individuals, which interfere with the effectiveness for cancer diagnostics. This study examined the background...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548860/ https://www.ncbi.nlm.nih.gov/pubmed/28790338 http://dx.doi.org/10.1038/s41598-017-06106-1 |