Statistical analysis of mutant allele frequency level of circulating cell-free DNA and blood cells in healthy individuals

Cell-free DNA (cfDNA) in plasma has emerged as a potential important biomarker in clinical diagnostics, particularly in cancer. However, somatic mutations are also commonly found in healthy individuals, which interfere with the effectiveness for cancer diagnostics. This study examined the background...

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Detalles Bibliográficos
Autores principales: Xia, Ligang, Li, Zhoufang, Zhou, Bo, Tian, Geng, Zeng, Lidong, Dai, Hongyu, Li, Xiaohua, Liu, Chaoyu, Lu, Shixin, Xu, Feiyue, Tu, Xiaonian, Deng, Fang, Xie, Yuancai, Huang, Weiren, He, Jiankui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548860/
https://www.ncbi.nlm.nih.gov/pubmed/28790338
http://dx.doi.org/10.1038/s41598-017-06106-1

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