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A DNA-centered explanation of the DNA polymerase translocation mechanism
DNA polymerase couples chemical energy to translocation along a DNA template with a specific directionality while it replicates genetic information. According to single-molecule manipulation experiments, the polymerase-DNA complex can work against loads greater than 50 pN. It is not known, on the on...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548866/ https://www.ncbi.nlm.nih.gov/pubmed/28790383 http://dx.doi.org/10.1038/s41598-017-08038-2 |