Selective cytotoxicity of a novel immunotoxin based on pulchellin A chain for cells expressing HIV envelope

Immunotoxins (ITs), which consist of antibodies conjugated to toxins, have been proposed as a treatment for cancer and chronic infections. To develop and improve the ITs, different toxins such as ricin, have been used, aiming for higher efficacy against target cells. The toxin pulchellin, isolated f...

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Detalles Bibliográficos
Autores principales: Sadraeian, Mohammad, Guimarães, Francisco E. G., Araújo, Ana P. U., Worthylake, David K., LeCour, Louis Jr., Pincus, Seth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548917/
https://www.ncbi.nlm.nih.gov/pubmed/28790381
http://dx.doi.org/10.1038/s41598-017-08037-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548917/
https://www.ncbi.nlm.nih.gov/pubmed/28790381
http://dx.doi.org/10.1038/s41598-017-08037-3

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