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Determination of the endothelin-1 recognition sites of endothelin receptor type A by the directed-degeneration method

G-protein coupled receptors (GPCRs) play indispensable physiological roles in cell proliferation, differentiation, and migration; therefore, identifying the mechanisms by which ligands bind to GPCRs is crucial for developing GPCR-targeting pharmaceutics and for understanding critical biological func...

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Detalles Bibliográficos
Autores principales: Han, Seong-Gu, Ko, Sanghwan, Lee, Won-Kyu, Jung, Sang Taek, Yu, Yeon Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548930/
https://www.ncbi.nlm.nih.gov/pubmed/28790412
http://dx.doi.org/10.1038/s41598-017-08096-6