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Optimization and validation of sample preparation for metagenomic sequencing of viruses in clinical samples
BACKGROUND: Sequence-specific PCR is the most common approach for virus identification in diagnostic laboratories. However, as specific PCR only detects pre-defined targets, novel virus strains or viruses not included in routine test panels will be missed. Recently, advances in high-throughput seque...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549297/ https://www.ncbi.nlm.nih.gov/pubmed/28789678 http://dx.doi.org/10.1186/s40168-017-0317-z |