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Tri-methylation of H3K79 is decreased in TGF-β1-induced epithelial-to-mesenchymal transition in lung cancer

BACKGROUND: The epithelial-to-mesenchymal transition (EMT) enables epithelial cancer cells to acquire mesenchymal features and contributes to metastasis and resistance to treatment. This process involves epigenetic reprogramming for gene expression. We explored global histone modifications during TG...

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Detalles Bibliográficos
Autores principales: Evanno, Emilie, Godet, Julie, Piccirilli, Nathalie, Guilhot, Joëlle, Milin, Serge, Gombert, Jean Marc, Fouchaq, Benoit, Roche, Joëlle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549304/
https://www.ncbi.nlm.nih.gov/pubmed/28804523
http://dx.doi.org/10.1186/s13148-017-0380-0