Serum high mobility group box-1 and osteoprotegerin levels are associated with peripheral arterial disease and critical limb ischemia in type 2 diabetic subjects

BACKGROUND: High mobility group box-1 (HMGB-1) is a nuclear protein also acting as inflammatory mediator, whilst osteoprotegerin (OPG), member of tumor necrosis factor receptor superfamily, is indicated as marker of vascular calcification. Peripheral artery disease (PAD) and type 2 diabetes (T2D) ar...

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Detalles Bibliográficos
Autores principales: Giovannini, Silvia, Tinelli, Giovanni, Biscetti, Federico, Straface, Giuseppe, Angelini, Flavia, Pitocco, Dario, Mucci, Luciana, Landolfi, Raffaele, Flex, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549317/
https://www.ncbi.nlm.nih.gov/pubmed/28789654
http://dx.doi.org/10.1186/s12933-017-0581-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549317/
https://www.ncbi.nlm.nih.gov/pubmed/28789654
http://dx.doi.org/10.1186/s12933-017-0581-z

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