A novel bladder cancer - specific oncolytic adenovirus by CD46 and its effect combined with cisplatin against cancer cells of CAR negative expression

BACKGROUND: Conditionally replicative oncolytic adenoviruses (CRAds) display significant anti-tumor effects. However, the traditional adenovirus of serotype 5 (Ad5) entering cancer cells via coxsackie virus and adenovirus receptor (CAR) can’t be utilized for bladder cancer with low expression of CAR...

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Detalles Bibliográficos
Autores principales: Cao, Wenjuan, Tian, Junqiang, Li, Chong, Gao, Yanjun, Liu, Xingchen, Lu, Jianzhong, Wang, Yuhan, Wang, Zhiping, Svatek, Robert S., Rodriguez, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549334/
https://www.ncbi.nlm.nih.gov/pubmed/28789701
http://dx.doi.org/10.1186/s12985-017-0818-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549334/
https://www.ncbi.nlm.nih.gov/pubmed/28789701
http://dx.doi.org/10.1186/s12985-017-0818-1

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