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A Humanized Ossicle-niche Xenotransplantation Model Enables Improved Human Leukemic Engraftment

Xenotransplantation models provide powerful tools for the investigation of human normal and malignant hematopoiesis. However, current models do not extensively recapitulate human bone marrow (BM) microenvironment components and exhibit limited engraftment of many human leukemias and other disorders....

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Detalles Bibliográficos
Autores principales: Reinisch, Andreas, Thomas, Daniel, Corces, M. Ryan, Zhang, Xiaohua, Gratzinger, Dita, Hong, Wan-Jen, Schallmoser, Katharina, Strunk, Dirk, Majeti, Ravindra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549556/
https://www.ncbi.nlm.nih.gov/pubmed/27213817
http://dx.doi.org/10.1038/nm.4103