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A Humanized Ossicle-niche Xenotransplantation Model Enables Improved Human Leukemic Engraftment
Xenotransplantation models provide powerful tools for the investigation of human normal and malignant hematopoiesis. However, current models do not extensively recapitulate human bone marrow (BM) microenvironment components and exhibit limited engraftment of many human leukemias and other disorders....
Autores principales: | Reinisch, Andreas, Thomas, Daniel, Corces, M. Ryan, Zhang, Xiaohua, Gratzinger, Dita, Hong, Wan-Jen, Schallmoser, Katharina, Strunk, Dirk, Majeti, Ravindra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549556/ https://www.ncbi.nlm.nih.gov/pubmed/27213817 http://dx.doi.org/10.1038/nm.4103 |
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