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CD205-TLR9-IL-12 axis contributes to CpG-induced oversensitive liver injury in HBsAg transgenic mice by promoting the interaction of NKT cells with Kupffer cells

Gut-derived bacterial products contribute to liver inflammation and injury during chronic hepatitis B virus infection; however, the underlying mechanisms remain obscure. In this study, hepatitis B surface antigen transgenic (HBs-Tg) mice and their wild-type (WT) control C57BL/6 mice were injected wi...

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Detalles Bibliográficos
Autores principales: Hou, Xin, Hao, Xiaolei, Zheng, Meijuan, Xu, Congfei, Wang, Jun, Zhou, Rongbin, Tian, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549602/
https://www.ncbi.nlm.nih.gov/pubmed/27041637
http://dx.doi.org/10.1038/cmi.2015.111