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Mitochondrial ROS regulate thermogenic energy expenditure and sulfenylation of UCP1

Brown adipose tissue (BAT) can dissipate chemical energy as heat through thermogenic respiration, which requires uncoupling protein 1 (UCP1)(1,2). Thermogenesis from BAT and beige adipose can combat obesity and diabetes(3), encouraging investigation of factors that control UCP1-dependent respiration...

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Detalles Bibliográficos
Autores principales: Chouchani, Edward T., Kazak, Lawrence, Jedrychowski, Mark P., Lu, Gina Z., Erickson, Brian K., Szpyt, John, Pierce, Kerry A., Laznik-Bogoslavski, Dina, Vetrivelan, Ramalingam, Clish, Clary B., Robinson, Alan J., Gygi, Steve P., Spiegelman, Bruce M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549630/
https://www.ncbi.nlm.nih.gov/pubmed/27027295
http://dx.doi.org/10.1038/nature17399