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Genetic risk in chronic pancreatitis: the misfolding-dependent pathway

Genetic risk in chronic pancreatitis is partly due to mutations that cause misfolding of digestive enzymes and elicit endoplasmic reticulum stress. This review examines recent developments in this concept. RECENT FINDINGS: The best characterized misfolding variants in the highly expressed digestive...

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Detalles Bibliográficos
Autor principal: Sahin-Tóth, Miklós
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549634/
https://www.ncbi.nlm.nih.gov/pubmed/28650851
http://dx.doi.org/10.1097/MOG.0000000000000380