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Genetic risk in chronic pancreatitis: the misfolding-dependent pathway
Genetic risk in chronic pancreatitis is partly due to mutations that cause misfolding of digestive enzymes and elicit endoplasmic reticulum stress. This review examines recent developments in this concept. RECENT FINDINGS: The best characterized misfolding variants in the highly expressed digestive...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Lippincott Williams & Wilkins
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549634/ https://www.ncbi.nlm.nih.gov/pubmed/28650851 http://dx.doi.org/10.1097/MOG.0000000000000380 |