Comprehensive spectral identification of key intermediates to the final product of the chiral pool synthesis of radezolid

Radezolid (RAD, 12), biaryl oxazolidinone, was synthesised with small modifications according to the methods described in the literature. The pharmacological activity is observed only for (S)-enantiomer, therefore its synthesis is oriented towards obtaining a single isomer of required purity and des...

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Detalles Bibliográficos
Autores principales: Michalska, Katarzyna, Bednarek, Elżbieta, Gruba, Ewa, Lewandowska, Kornelia, Mizera, Mikołaj, Cielecka-Piontek, Judyta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549672/
https://www.ncbi.nlm.nih.gov/pubmed/29086862
http://dx.doi.org/10.1186/s13065-017-0309-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549672/
https://www.ncbi.nlm.nih.gov/pubmed/29086862
http://dx.doi.org/10.1186/s13065-017-0309-x

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