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Comprehensive spectral identification of key intermediates to the final product of the chiral pool synthesis of radezolid
Radezolid (RAD, 12), biaryl oxazolidinone, was synthesised with small modifications according to the methods described in the literature. The pharmacological activity is observed only for (S)-enantiomer, therefore its synthesis is oriented towards obtaining a single isomer of required purity and des...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549672/ https://www.ncbi.nlm.nih.gov/pubmed/29086862 http://dx.doi.org/10.1186/s13065-017-0309-x |