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History of antibiotic adaptation influences microbial evolutionary dynamics during subsequent treatment
Antibiotic regimens often include the sequential changing of drugs to limit the development and evolution of resistance of bacterial pathogens. It remains unclear how history of adaptation to one antibiotic can influence the resistance profiles when bacteria subsequently adapt to a different antibio...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549691/ https://www.ncbi.nlm.nih.gov/pubmed/28792497 http://dx.doi.org/10.1371/journal.pbio.2001586 |