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Cryptosporidium parvum vaccine candidates are incompletely modified with O-linked-N-acetylgalactosamine or contain N-terminal N-myristate and S-palmitate

Cryptosporidium parvum (studied here) and Cryptosporidium hominis are important causes of diarrhea in infants and immunosuppressed persons. C. parvum vaccine candidates, which are on the surface of sporozoites, include glycoproteins with Ser- and Thr-rich domains (Gp15, Gp40, and Gp900) and a low co...

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Detalles Bibliográficos
Autores principales: Haserick, John R., Klein, Joshua A., Costello, Catherine E., Samuelson, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549699/
https://www.ncbi.nlm.nih.gov/pubmed/28792526
http://dx.doi.org/10.1371/journal.pone.0182395