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Distinct age and differentiation-state dependent metabolic profiles of oligodendrocytes under optimal and stress conditions

Within the microenvironment of multiple sclerosis lesions, oligodendrocytes are subject to metabolic stress reflecting effects of focal ischemia and inflammation. Previous studies have shown that under optimal conditions in vitro, the respiratory activity of human adult brain-derived oligodendrocyte...

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Detalles Bibliográficos
Autores principales: Rao, Vijayaraghava T. S., Khan, Damla, Cui, Qiao-Ling, Fuh, Shih-Chieh, Hossain, Shireen, Almazan, Guillermina, Multhaup, Gerhard, Healy, Luke M., Kennedy, Timothy E., Antel, Jack P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549710/
https://www.ncbi.nlm.nih.gov/pubmed/28792512
http://dx.doi.org/10.1371/journal.pone.0182372