The mecillinam resistome reveals a role for peptidoglycan endopeptidases in stimulating cell wall synthesis in Escherichia coli

Bacterial cells are typically surrounded by an net-like macromolecule called the cell wall constructed from the heteropolymer peptidoglycan (PG). Biogenesis of this matrix is the target of penicillin and related beta-lactams. These drugs inhibit the transpeptidase activity of PG synthases called pen...

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Detalles Bibliográficos
Autores principales: Lai, Ghee Chuan, Cho, Hongbaek, Bernhardt, Thomas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549755/
https://www.ncbi.nlm.nih.gov/pubmed/28749938
http://dx.doi.org/10.1371/journal.pgen.1006934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549755/
https://www.ncbi.nlm.nih.gov/pubmed/28749938
http://dx.doi.org/10.1371/journal.pgen.1006934

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