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Control of RUNX-induced repression of Notch signaling by MLF and its partner DnaJ-1 during Drosophila hematopoiesis

A tight regulation of transcription factor activity is critical for proper development. For instance, modifications of RUNX transcription factors dosage are associated with several diseases, including hematopoietic malignancies. In Drosophila, Myeloid Leukemia Factor (MLF) has been shown to control...

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Detalles Bibliográficos
Autores principales: Miller, Marion, Chen, Aichun, Gobert, Vanessa, Augé, Benoit, Beau, Mathilde, Burlet-Schiltz, Odile, Haenlin, Marc, Waltzer, Lucas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549762/
https://www.ncbi.nlm.nih.gov/pubmed/28742844
http://dx.doi.org/10.1371/journal.pgen.1006932