SIRT1 Enhances the Survival of Human Embryonic Stem Cells by Promoting DNA Repair

Human embryonic stem cells (hESCs) hold great promise for the treatment of many incurable diseases. Sirtuin1 (SIRT1), a class III histone deacetylase, is abundantly expressed in hESCs and is known to regulate early differentiation and telomere elongation. Here, we show that downregulation of SIRT1 p...

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Detalles Bibliográficos
Autores principales: Jang, Jiho, Huh, Yong Jun, Cho, Hyun-Ju, Lee, Boram, Park, Jaepil, Hwang, Dong-Youn, Kim, Dong-Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549766/
https://www.ncbi.nlm.nih.gov/pubmed/28689995
http://dx.doi.org/10.1016/j.stemcr.2017.06.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549766/
https://www.ncbi.nlm.nih.gov/pubmed/28689995
http://dx.doi.org/10.1016/j.stemcr.2017.06.001

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