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SIRT1 Enhances the Survival of Human Embryonic Stem Cells by Promoting DNA Repair

Human embryonic stem cells (hESCs) hold great promise for the treatment of many incurable diseases. Sirtuin1 (SIRT1), a class III histone deacetylase, is abundantly expressed in hESCs and is known to regulate early differentiation and telomere elongation. Here, we show that downregulation of SIRT1 p...

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Detalles Bibliográficos
Autores principales:	Jang, Jiho, Huh, Yong Jun, Cho, Hyun-Ju, Lee, Boram, Park, Jaepil, Hwang, Dong-Youn, Kim, Dong-Wook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549766/ https://www.ncbi.nlm.nih.gov/pubmed/28689995 http://dx.doi.org/10.1016/j.stemcr.2017.06.001

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