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Human cytomegalovirus IE1 downregulates Hes1 in neural progenitor cells as a potential E3 ubiquitin ligase

Congenital human cytomegalovirus (HCMV) infection is the leading cause of neurological disabilities in children worldwide, but the mechanisms underlying these disorders are far from well-defined. HCMV infection has been shown to dysregulate the Notch signaling pathway in human neural progenitor cell...

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Detalles Bibliográficos
Autores principales: Liu, Xi-Juan, Yang, Bo, Huang, Sheng-Nan, Wu, Cong-Cong, Li, Xiao-Jun, Cheng, Shuang, Jiang, Xuan, Hu, Fei, Ming, Ying-Zi, Nevels, Michael, Britt, William J., Rayner, Simon, Tang, Qiyi, Zeng, Wen-Bo, Zhao, Fei, Luo, Min-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549770/
https://www.ncbi.nlm.nih.gov/pubmed/28750047
http://dx.doi.org/10.1371/journal.ppat.1006542