Cargando…
Human cytomegalovirus IE1 downregulates Hes1 in neural progenitor cells as a potential E3 ubiquitin ligase
Congenital human cytomegalovirus (HCMV) infection is the leading cause of neurological disabilities in children worldwide, but the mechanisms underlying these disorders are far from well-defined. HCMV infection has been shown to dysregulate the Notch signaling pathway in human neural progenitor cell...
Autores principales: | Liu, Xi-Juan, Yang, Bo, Huang, Sheng-Nan, Wu, Cong-Cong, Li, Xiao-Jun, Cheng, Shuang, Jiang, Xuan, Hu, Fei, Ming, Ying-Zi, Nevels, Michael, Britt, William J., Rayner, Simon, Tang, Qiyi, Zeng, Wen-Bo, Zhao, Fei, Luo, Min-Hua |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549770/ https://www.ncbi.nlm.nih.gov/pubmed/28750047 http://dx.doi.org/10.1371/journal.ppat.1006542 |
Ejemplares similares
-
Human Cytomegalovirus Genomes Survive Mitosis via the IE19 Chromatin-Tethering Domain
por: Lyon, Shelby M., et al.
Publicado: (2020) -
Hyperhomocysteinemia induces injury in olfactory bulb neurons by downregulating Hes1 and Hes5 expression
por: Zhang, Jing-wen, et al.
Publicado: (2018) -
Downregulation of the ubiquitin ligase KBTBD8 prevented epithelial ovarian cancer progression
por: Du, Lei, et al.
Publicado: (2020) -
Human Cytomegalovirus IE1 Protein Elicits a Type II Interferon-Like
Host Cell Response That Depends on Activated STAT1 but Not
Interferon-γ
por: Knoblach, Theresa, et al.
Publicado: (2011) -
Human Cytomegalovirus IE2 Disrupts Neural Progenitor Development and Induces Microcephaly in Transgenic Mouse
por: Niu, Delei, et al.
Publicado: (2023)