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Effects of thrombin, PAR-1 activating peptide and a PAR-1 antagonist on umbilical artery resistance in vitro

BACKGROUND: The non-thrombotic effects of thrombin in cardiovascular tissues, as mediated via the protease activated receptors (PARs), and particularly PAR-1, have been the focus of much recent research. The aims of this study were to evaluate the effects of thrombin, a specific PAR-1 activating pep...

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Detalles Bibliográficos
Autores principales: O'Loughlin, Aonghus J, O'Sullivan, Crochan J, Ravikumar, Nandini, Friel, Anne M, Elliott, John T, Morrison, John J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC554978/
https://www.ncbi.nlm.nih.gov/pubmed/15730558
http://dx.doi.org/10.1186/1477-7827-3-8