A Short Region of Connexin43 Reduces Human Glioma Stem Cell Migration, Invasion, and Survival through Src, PTEN, and FAK

Connexin43 (CX43), a protein that forms gap junction channels and hemichannels in astrocytes, is downregulated in high-grade gliomas. Its relevance for glioma therapy has been thoroughly explored; however, its positive effects on proliferation are counterbalanced by its effects on migration and inva...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaraíz-Rodríguez, Myriam, Tabernero, Ma Dolores, González-Tablas, María, Otero, Alvaro, Orfao, Alberto, Medina, Jose M., Tabernero, Arantxa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549880/
https://www.ncbi.nlm.nih.gov/pubmed/28712848
http://dx.doi.org/10.1016/j.stemcr.2017.06.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549880/
https://www.ncbi.nlm.nih.gov/pubmed/28712848
http://dx.doi.org/10.1016/j.stemcr.2017.06.007

Ejemplares similares