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Aberrant cGMP signaling persists during recovery in mice with oxygen-induced pulmonary hypertension

Bronchopulmonary dysplasia (BPD), a common complication of preterm birth, is associated with pulmonary hypertension (PH) in 25% of infants with moderate to severe BPD. Neonatal mice exposed to hyperoxia for 14d develop lung disease similar to BPD, with evidence of associated PH. The cyclic guanosine...

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Detalles Bibliográficos
Autores principales: Perez, Marta, Lee, Keng Jin, Cardona, Herminio J., Taylor, Joann M., Robbins, Mary E., Waypa, Gregory B., Berkelhamer, Sara K., Farrow, Kathryn N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549891/
https://www.ncbi.nlm.nih.gov/pubmed/28792962
http://dx.doi.org/10.1371/journal.pone.0180957