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A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin

The presence of dark melanin (eumelanin) within human epidermis represents one of the strongest predictors of low skin cancer risk. Topical rescue of eumelanin synthesis, previously achieved in “redhaired” Mc1r-deficient mice, demonstrated significant protection against UV damage. However, applicati...

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Detalles Bibliográficos
Autores principales: Mujahid, Nisma, Liang, Yanke, Murakami, Ryo, Choi, Hwan Geun, Dobry, Allison S., Wang, Jinhua, Suita, Yusuke, Weng, Qing Yu, Allouche, Jennifer, Kemeny, Lajos V., Hermann, Andrea L., Roider, Elisabeth M., Gray, Nathanael S., Fisher, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549921/
https://www.ncbi.nlm.nih.gov/pubmed/28614705
http://dx.doi.org/10.1016/j.celrep.2017.05.042