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Using the MWC model to describe heterotropic interactions in hemoglobin

Hemoglobin is a classical model allosteric protein. Research on hemoglobin parallels the development of key cooperativity and allostery concepts, such as the ‘all-or-none’ Hill formalism, the stepwise Adair binding formulation and the concerted Monod-Wymann-Changuex (MWC) allosteric model. While it...

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Detalles Bibliográficos
Autores principales: Rapp, Olga, Yifrach, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549968/
https://www.ncbi.nlm.nih.gov/pubmed/28793329
http://dx.doi.org/10.1371/journal.pone.0182871