Reduced internalization of TNF-ɑ/TNFR1 down-regulates caspase dependent phagocytosis induced cell death (PICD) in neonatal monocytes

Phagocytosis-induced cell death (PICD) is diminished in cord blood monocytes (CBMO) as compared to cells from adults (PBMO) due to differences in the CD95-pathway. This may support a prolonged pro-inflammatory response with sequels of sustained inflammation as seen in neonatal sepsis. Here we hypoth...

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Detalles Bibliográficos
Autores principales: Dreschers, Stephan, Gille, Christian, Haas, Martin, Seubert, Florence, Platen, Christopher, Orlikowsky, Thorsten W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549969/
https://www.ncbi.nlm.nih.gov/pubmed/28793310
http://dx.doi.org/10.1371/journal.pone.0182415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549969/
https://www.ncbi.nlm.nih.gov/pubmed/28793310
http://dx.doi.org/10.1371/journal.pone.0182415

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