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Detecting epistasis with the marginal epistasis test in genetic mapping studies of quantitative traits

Epistasis, commonly defined as the interaction between multiple genes, is an important genetic component underlying phenotypic variation. Many statistical methods have been developed to model and identify epistatic interactions between genetic variants. However, because of the large combinatorial se...

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Detalles Bibliográficos
Autores principales: Crawford, Lorin, Zeng, Ping, Mukherjee, Sayan, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550000/
https://www.ncbi.nlm.nih.gov/pubmed/28746338
http://dx.doi.org/10.1371/journal.pgen.1006869