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Automated incorporation of pairwise dependency in transcription factor binding site prediction using dinucleotide weight tensors
Gene regulatory networks are ultimately encoded by the sequence-specific binding of (TFs) to short DNA segments. Although it is customary to represent the binding specificity of a TF by a position-specific weight matrix (PSWM), which assumes each position within a site contributes independently to t...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550003/ https://www.ncbi.nlm.nih.gov/pubmed/28753602 http://dx.doi.org/10.1371/journal.pcbi.1005176 |